New Physical–Mathematical Analysis of Cardiac Dynamics and Temperature for the Diagnosis of Infectious Disease

Abstract

Background: Physical and mathematical theories have made it possible to generate methods for the characterization and diagnosis of physiological variables such as cardiac dynamics. Therefore, it would be useful to implement them to evaluate the dynamic changes in human physiology during the development of COVID-19, which causes disease, severe respiratory and death. Objective: to establish a method for detecting possible alterations associated with COVID-19 through simulations of adult cardiac dynamics and body temperature using dynamic systems theory, probability, entropy and set theory. Methodology: simulations of cardiac dynamics were generated in subjects with 10 temperature ranges between 32 °C and 42 °C via numerical attractors after their evaluation using entropy proportions. Results: differences were observed in the proportions of entropy that differentiate normal cardiac dynamics and acute myocardial infarction towards progression to fever. Conclusion: the physical mathematical analysis of cardiac behavior in relation to body temperature in people with COVID-19 allowed the establishment of a possible surveillance method for detecting minor alterations.

Keywords

• COVID-19
• probability
• fractal
• entropy
• simulation