Sakarya Tıp Dergisi (Jun 2018)

Assessment of the Relationship Between Leukocyte Count and Neutrophil-to-Lymphocyte Ratio and Clinical Course in Non-Variceal Upper Gastrointestinal System Bleeding

  • Mevlüt Türe,
  • Altay Kandemir,
  • Mehmet Süle,
  • İrfan Yavaşoğlu,
  • Adil Coşkun,
  • Abdülvahit Yükselen,
  • M. Hadi Yaşa

DOI
https://doi.org/10.31832/smj.414202
Journal volume & issue
Vol. 8, no. 2
pp. 320 – 326

Abstract

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Objective: Nonvariceal upper gastrointestinal system bleeding (NVUGIB) is a life-threatening condition that can lead to mortality. It is important to identify the risk factors in terms of prognosis and mortality in patients with NVUGIB. In this study, we assessed the relationship between leukocytosis and neutrophil-to-lymphocyte ratio and the clinical course in patients with NVUGIB.Materials and Methods: We included 156 patients who were diagnosed with NVUGIB between September 2013 and March 2017 in our clinic. The relationship between demographic data, endoscopic findings, need for erythrocyte suspension, length of hospital stay, need for intensive care, need for surgical intervention and mortality of the patients with the number of leukocytes and neutrophil-to-lymphocyte ratio (NLR) was investigated.Results: Of the patients, 104 (66,7%) were male, 52 (33,3%) were female, and mean age was 63,8±17,6 years. According to endoscopic findings, the most common cause of the bleeding was peptic ulcer (77,6%). There was no statistically significant correlation between leukocyte count and NLR and need for intensive care, need for surgical intervention and treatment outcome. However, there was a statistically significant relationship between NLR and length of hospital stay (p=0,02) Conclusions: Evaluation of the patients with NVUGIB timely through their findings detected at admission and their laboratory results would make a positive contribution to treatment planning and follow up of the patient. Leukocyte count alone or in combination with other clinical and laboratory parameters can be a valuable marker in measuring mortality potential of acutely hospitalized patients. In our study, we found a significant relationship between NLR and the average length of hospital stay, which should be encouraged for further studies investigating its relation with the prognosis of the disease.

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