Brazilian Neurosurgery (Mar 2024)

Hypotension and Bradycardia Following Papaverine Installation During Intracranial Aneurysm Surgery: A Report of Three Cases

  • Zahraa F. Al-Sharshahi,
  • Samer S. Hoz,
  • Mustafa E. Almurayati,
  • Teeba M. Ghanim,
  • Zahraa M. Kareem,
  • Zahraa A. Alsubaihawi

DOI
https://doi.org/10.1055/s-0041-1730371
Journal volume & issue
Vol. 43, no. 01
pp. e65 – e68

Abstract

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Introduction One of the major complications of intracranial aneurysm surgery is vasospasm. Papaverine is an effective vasodilator that can be instilled directly onto the vessels in the operative field with the aim of preventing intraoperative and postoperative vasospasm. Several case reports of hemodynamic instability in general and of hypotension, in particular, were reported after the use of topical papaverine during aneurysm clipping surgery.

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