Parkinsonism in in the Yaroslavl region: clinico-epidemiological aspects and a working experience of a specialized center

Abstract

The objective: to explore clinico-epidemiological aspects ofparkinsonism in the Yaroslavl region. One thousand patientswere examined in the movement disorders outpatient clinics in20072010. We used standard criteria for the diagnostics ofextrapyramidal disorders and the following scales: UPDRS,HoehnYahr and SchwabEngland. On observation, 53% ofpatients were from Yaroslavl and 37% from the Yaroslavl region.474 (47%) patients were diagnosed with Parkinson disease, 62(6.2%) with vascular parkinsonism, 17 (1.7%) with parkinsonism-plus, 8 (0.8%) with neuroleptic parkinsonism, 1 (0.1%) withpost-encephalitic parkinsonism and 1 (0.1%) with parkinsonismcaused by brain tumor. Women prevailed among Parkinsons diseasepatients (1 : 1.5). Most patients (71%) were from 60 to 75years of age. 18% of patients had stage 5 of PD, 50% had stage 2,27% had stage 3 and 5% had stage 4. A mixed form of the diseaseprevailed (71%); an akinetic-rigid form (23%) and a tremblingform (5%) occurred more rarely. In 58% of patients an intermediaterate of progression was observed, in 22% of patients progressionwas rapid and in 20% of patients it was slow. In general,our results correspond to international findings. Activity of aspecialized movement disorders center improve diagnostics,treatment and quality of life of patients with Parkinsons disease.

Keywords

• parkinsonism
• epidemiology
• clinics
• yaroslavl region
• specialized center