Nature Communications (Oct 2022)

Genomic insights into the physiology of Quinella, an iconic uncultured rumen bacterium

  • Sandeep Kumar,
  • Eric Altermann,
  • Sinead C. Leahy,
  • Ruy Jauregui,
  • Arjan Jonker,
  • Gemma Henderson,
  • Sandra Kittelmann,
  • Graeme T. Attwood,
  • Janine Kamke,
  • Sinéad M. Waters,
  • Mark L. Patchett,
  • Peter H. Janssen

DOI
https://doi.org/10.1038/s41467-022-34013-1
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 13

Abstract

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Uncultured bacteria of the genus Quinella are found in the rumen of ruminant animals, especially in sheep that emit low amounts of methane. Here, Kumar et al. reconstruct genomic sequences from Quinella cells to provide insights into their metabolic capabilities, including lactate and propionate formation as major fermentation pathways and an apparent lack of production of H2, a major precursor of methane.