Nature Communications (Jun 2021)

Vapor-phased fabrication and modulation of cell-laden scaffolding materials

  • Chih-Yu Wu,
  • Ting-Ying Wu,
  • Zhen-Yu Guan,
  • Peng-Yuan Wang,
  • Yen-Ching Yang,
  • Chao-Wei Huang,
  • Tzu-Hung Lin,
  • Hsien-Yeh Chen

DOI
https://doi.org/10.1038/s41467-021-23776-8
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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Current methods for the modular assembly of biomaterials are associated with limitations. Here the authors implement vapor-phase deposition to fabricate 3D polymeric materials that permit biomolecule functionalization, tunable mass transport and mechanical properties, as well as control over boundaries between compartments, and analyze the behavior of 3D encapsulated cells.