Observation on the efficacy of Mitomycin C for patients with refractory glaucoma and its influence on the serum vitamin and interleukin

Abstract

AIM: To investigate the efficacy of Mitomycin C(MMC)for patients with refractory glaucoma and its influence on the serum vitamin and interleukin. METHODS: Patients with refractory glaucoma from January 2010 to January 2013 were randomly divided into control group(compound trabeculectomy treatment group)with 80 cases and observation group(MMC combined with compound trabeculectomy treatment group)with 80 cases, then the difference in efficacy between the two groups were counted, and the intraocular pressure, visual acuity and the levels of FA, VB12, VB6, IL-2 and IL-6 of two groups before and after the treatment were also been compared. RESULTS: The surgical success rate of observation group was 80.9% which was significantly higher than that of control group(60.7%); after the surgery, the intraocular pressure of observation group were all lower than that of control group, and the visual acuity was better than that of control group, all PPPCONCLUSION: Combined with MMC could effectively improve surgical success rate of refractory glaucoma, and improve the indicators of serum vitamin, interleukin.

Keywords

• Mitomycin C
• refractory glaucoma
• vitamin
• interleukin
• interleukin