Journal of the Brazilian Chemical Society (Jan 1998)

Synthesis of the Novel 4,4?- and 6,6?- Dihydroxamic - 2,2?-Bipyridines and Improved Routes to 4,4?- and 6,6?- Substituted 2,2?-Bipyridines and Mono-N-Oxide-2,2?-Bipyridine

  • Donnici Claudio Luis,
  • Máximo Filho Daniel Henrique,
  • Moreira Leda Lúcia Cruz,
  • Reis Genuína Teixeira dos,
  • Cordeiro Estefania Santos,
  • Oliveira Ione Ma. Ferreira de,
  • Carvalho Sandra,
  • Paniago Eucler B.

Journal volume & issue
Vol. 9, no. 5
pp. 455 – 460

Abstract

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The preparation of key precursors for many 2,2?-bipyridine derivatives such as 4,4?-dicarboxy- 2,2?-bipyridine (I), 6,6?-dicarboxy-2,2?-bipyridine- acid (II), 4,4?-dinitro-2,2?-bipyridine-N,N-dioxide (III), 6,6?-dicarbothioamide-2,2?-bipyridine (IV) and mono-N-oxide-2,2?-bipyridine (VII) through more efficient methods is described. The syntheses of the novel ligands 4,4?-dihydroxamic-2,2?-bipyridine (V) and 6,6?-dihydroxamic-2,2?-bipyridine (VI) are also reported.

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