Cryo-EM structure of ssDNA bacteriophage ΦCjT23 provides insight into early virus evolution

Nejc Kejzar; Elina Laanto; Ilona Rissanen; Vahid Abrishami; Muniyandi Selvaraj; Sylvain Moineau; Janne Ravantti; Lotta-Riina Sundberg; Juha T. Huiskonen

doi:10.1038/s41467-022-35123-6

Nature Communications (Dec 2022)

Cryo-EM structure of ssDNA bacteriophage ΦCjT23 provides insight into early virus evolution

Nejc Kejzar,
Elina Laanto,
Ilona Rissanen,
Vahid Abrishami,
Muniyandi Selvaraj,
Sylvain Moineau,
Janne Ravantti,
Lotta-Riina Sundberg,
Juha T. Huiskonen

Affiliations

Nejc Kejzar: Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, University of Helsinki
Elina Laanto: Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki
Ilona Rissanen: Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, University of Helsinki
Vahid Abrishami: Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, University of Helsinki
Muniyandi Selvaraj: Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, University of Helsinki
Sylvain Moineau: Département de biochimie, de microbiologie, et de bio-informatique, Université Laval, Québec City
Janne Ravantti: Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki
Lotta-Riina Sundberg: Department of Biological and Environmental Science, Nanoscience Center, University of Jyväskylä
Juha T. Huiskonen: Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, University of Helsinki

DOI: https://doi.org/10.1038/s41467-022-35123-6
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 13

Abstract

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Structural biology investigation of conserved capsid proteins facilitates the study of virus evolution. Here, characterization of the lipid-containing ssDNA bacteriophage ΦCjT23 suggests that this phage may serve as a model for the last common ancestor between ssDNA and dsDNA viruses in the Bamfordvirae.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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