International Journal of Public Health (Jul 2023)
Retention and Predictors of Attrition Among People Living With HIV on Antiretroviral Therapy in Guinea: A 13-Year Historical Cohort Study in Nine Large-Volume Sites
- Niouma Nestor Leno,
- Niouma Nestor Leno,
- Niouma Nestor Leno,
- Foromo Guilavogui,
- Foromo Guilavogui,
- Foromo Guilavogui,
- Alioune Camara,
- Alioune Camara,
- Alioune Camara,
- Kadio Jean-Jacques Olivier Kadio,
- Timothé Guilavogui,
- Timothé Guilavogui,
- Thierno Saidou Diallo,
- Mamadou Aliou Diallo,
- Daniel William Athanase Leno,
- Button Ricarte,
- Youssouf Koita,
- Laye Kaba,
- Arnold Ahiatsi,
- Nagnouman Touré,
- Pascal Traoré,
- Souleymane Chaloub,
- André Kamano,
- Carlos Arias Vicente,
- Alexandre Delamou,
- Alexandre Delamou,
- Alexandre Delamou,
- Mohamed Cissé
Affiliations
- Niouma Nestor Leno
- African Center of Excellence for Prevention and Control of Communicable Diseases (CEA-PCMT), Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University, Conakry, Guinea
- Niouma Nestor Leno
- Department of Public Health, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University Conakry, Conakry, Guinea
- Niouma Nestor Leno
- Ministry of Health, Conakry, Guinea
- Foromo Guilavogui
- Department of Public Health, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University Conakry, Conakry, Guinea
- Foromo Guilavogui
- Ministry of Health, Conakry, Guinea
- Foromo Guilavogui
- National AIDS and Hepatitis Control Program, Conakry, Guinea
- Alioune Camara
- African Center of Excellence for Prevention and Control of Communicable Diseases (CEA-PCMT), Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University, Conakry, Guinea
- Alioune Camara
- Department of Public Health, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University Conakry, Conakry, Guinea
- Alioune Camara
- National Malaria Control Program, Conakry, Guinea
- Kadio Jean-Jacques Olivier Kadio
- Center of Infectious Disease Research and Training, Gamal Abdel Nasser University of Conakry, Conakry, Guinea
- Timothé Guilavogui
- Department of Public Health, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University Conakry, Conakry, Guinea
- Timothé Guilavogui
- Ministry of Health, Conakry, Guinea
- Thierno Saidou Diallo
- National AIDS and Hepatitis Control Program, Conakry, Guinea
- Mamadou Aliou Diallo
- National AIDS and Hepatitis Control Program, Conakry, Guinea
- Daniel William Athanase Leno
- Gynaecology-Obstetrics Service, Donka National Hospital, Conakry, Guinea
- Button Ricarte
- Merck Group, Lyon, France
- Youssouf Koita
- National AIDS and Hepatitis Control Program, Conakry, Guinea
- Laye Kaba
- National AIDS and Hepatitis Control Program, Conakry, Guinea
- Arnold Ahiatsi
- National AIDS and Hepatitis Control Program, Conakry, Guinea
- Nagnouman Touré
- National AIDS and Hepatitis Control Program, Conakry, Guinea
- Pascal Traoré
- Department of Public Health, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University Conakry, Conakry, Guinea
- Souleymane Chaloub
- NGO “Doctors Without Borders Belgium”, Conakry, Guinea
- André Kamano
- NGO “Doctors Without Borders Belgium”, Conakry, Guinea
- Carlos Arias Vicente
- NGO “Doctors Without Borders Belgium”, Conakry, Guinea
- Alexandre Delamou
- African Center of Excellence for Prevention and Control of Communicable Diseases (CEA-PCMT), Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University, Conakry, Guinea
- Alexandre Delamou
- Department of Public Health, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University Conakry, Conakry, Guinea
- Alexandre Delamou
- 0National Center for Education and Research in Rural Health Maférinyah, Forécariah, Guinea
- Mohamed Cissé
- 1Department of Dermatology and Sexually Transmitted Infections, Gamal Abdel Nasser University of Conakry Faculty of Health Sciences and Techniques, Conakry, Guinea
- DOI
- https://doi.org/10.3389/ijph.2023.1605929
- Journal volume & issue
-
Vol. 68
Abstract
Objectives: The objective of this study was to estimate the retention rate of patients in an ART program and identify the predictors of attrition.Methods: This was a historical cohort study of HIV patients who started ART between September 2007 and April 2020, and were followed up on for at least 6 months in nine large-volume sites. Kaplan Meier techniques were used to estimate cumulative retention and attrition probabilities. Cox proportional hazards models were used to identify predictors of attrition.Results: The cumulative probability of retention at 12 and 24 months was 76.2% and 70.2%, respectively. The attrition rate after a median follow-up time of 3.1 years was 35.2%, or an incidence of 11.4 per 100 person-years. Having initiated ART between 2012 and 2015; unmarried status; having initiated ART with CD4 count <100 cells/μL; and having initiated ART at an advanced clinical stage were factors significantly associated with attrition.Conclusion: The retention rate in our study is much lower than the proposed national target (90%). Studies to understand the reasons for loss to follow-up are needed.
Keywords
