Case Reports in Pathology (Jan 2022)

Ectopic Fetal Liver Tissue in the Placenta of a Twin Pregnancy: A Case Report and Review of Literature

  • Andrei Leucă,
  • Pieter Demetter,
  • Amélie Boulay,
  • Katherina Vanden Houte,
  • Valérie Segers,
  • Laurine Verset

DOI
https://doi.org/10.1155/2022/1966025
Journal volume & issue
Vol. 2022

Abstract

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Ectopic liver tissue represents a rare entity and is mostly attributed to events occurring during embryogenesis. Previous case reports documented the presence of fetal liver parenchyma within temporarily developed organs during pregnancy, such as the placenta or the umbilical cord. Moreover, the terminology of these benign findings varies from “ectopic liver” to “hepatocellular adenoma-like neoplasm” or “hepatocellular adenoma”. Ancillary tests performed on these lesions have shown positive immunohistochemical staining for hepatocellular origin marker HepPar-1. Only one recent case report comprising molecular analysis showed no beta-catenin gain-of-function mutation. We report a case of ectopic liver in one placenta of a twin pregnancy, with an updated review of literature.