3D Printing of Tough Hydrogel Scaffolds with Functional Surface Structures for Tissue Regeneration

Ke Yao; Gaoying Hong; Ximin Yuan; Weicheng Kong; Pengcheng Xia; Yuanrong Li; Yuewei Chen; Nian Liu; Jing He; Jue Shi; Zihe Hu; Yanyan Zhou; Zhijian Xie; Yong He

doi:10.1007/s40820-024-01524-z

Nano-Micro Letters (Sep 2024)

3D Printing of Tough Hydrogel Scaffolds with Functional Surface Structures for Tissue Regeneration

Ke Yao,
Gaoying Hong,
Ximin Yuan,
Weicheng Kong,
Pengcheng Xia,
Yuanrong Li,
Yuewei Chen,
Nian Liu,
Jing He,
Jue Shi,
Zihe Hu,
Yanyan Zhou,
Zhijian Xie,
Yong He

Affiliations

Ke Yao: State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University
Gaoying Hong: Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine
Ximin Yuan: State Key Laboratory of Advanced Welding and Joining, Harbin Institute of Technology
Weicheng Kong: State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University
Pengcheng Xia: Institute of Digital Medicine, Nanjing First Hospital, Nanjing Medical University
Yuanrong Li: State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University
Yuewei Chen: State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University
Nian Liu: State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University
Jing He: State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University
Jue Shi: Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine
Zihe Hu: Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine
Yanyan Zhou: Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine
Zhijian Xie: Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine
Yong He: State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University

DOI: https://doi.org/10.1007/s40820-024-01524-z
Journal volume & issue: Vol. 17, no. 1
pp. 1 – 28

Abstract

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Highlights We propose the novel concept of a tough hydrogel scaffold within the realm of tissue engineering. This scaffold combines exceptional strength (6.66 MPa), customization capabilities, and superior biocompatibility in a manner not previously achieved in existing research. These tough hydrogel scaffolds possess functional surface structures and can effectively enhance cell-guided growth and prompt regeneration of muscle tissue in vivo. This is a universal manufacturing method for tough hydrogel scaffolds in tissue engineering.

Published in Nano-Micro Letters

ISSN: 2311-6706 (Print); 2150-5551 (Online)
Publisher: SpringerOpen
Country of publisher: Germany
LCC subjects: Technology
Website: http://www.springer.com/40820

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Abstract

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