Vestnik Transplantologii i Iskusstvennyh Organov (Jun 2010)

BIOCHEMICAL BONE MARKERS AS PREDICTORS OF BONE LOSSES FOLLOWING LIVER TRANSPLANTATION

  • V. P. Buzulina,
  • I. A. Pronchenko,
  • I. P. Yermakova,
  • E. B. Yaroshenko,
  • M. N. Kornilov,
  • N. P. Shmerko

DOI
https://doi.org/10.15825/1995-1191-2010-3-52-61
Journal volume & issue
Vol. 12, no. 3
pp. 52 – 61

Abstract

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24 recipients after ortotopic liver transplantation (9 women and 5 men) 18–57 years aged were studied in 1–2 and then through 4–18 months following operation. Bone mineral density (BMD) in repeated estimation in 13 recipients was elevated on 14 ± 10,5% and in 11 recipients was decreased on 2,5 ± 2,56%. BMD elevation was associated with bone remodelling normalization. BMD lowering followed transplant dysfunction, glucocorticoid therapy, bone resorption increasing and bone formation suppression.

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