N-Methyl-l-leucyl-l-leucine hydrochloride monohydrate

Abstract

In the title compound C13H27N2O3+·Cl−·H2O, obtained by deprotecting the amino and carboxyl groups of an intermediate in the synthesis of the cyclic pentapeptide Galaxamide, a number of hydrogen-bonding interactions occur including aminium N—H...Cl, amide–carboxyl N—H...O, water O—H...Cl and carboxyl–water O—H...O associations. The aminium N—H...Cl...H—N bridging extensions give rise to zigzag chains extending along the a axis, the overall two-dimensional structure lying in the (110) plane.