Morphological features of the lymphatic channel of lymph nodes of in Domestic Bull (Bos taurus)

Abstract

The morphological features patterns of the extra-organ and intra-nodal lymphatic channel in the domestic bull’s somatic lymph nodes were investigated. The method of indirect injection of lymphatic vessels a finely dispersed contrast mass (suspension of blue ink per 5 % solution (gel) gelatin) by interstitial administration was used. The distribution pattern of the contrast mass in the pre-nodal (afferent) lymphatic vessels, in the lymphatic intra-nodal collector and in the sinuses of the lymph nodes parenchyma was determined. It has been established that afferent lymphatic vessels on the surface of the lymph node capsule are divided into numerous branches that flow into the main lymphatic collector – the subcapsular sinus. The number of afferent lymphatic vessels branches corresponds to the number of the subunits of parenchyma’s lobules, the number of which is characteristic of each individual lymph node. Externally the parenchyma’s lobules in the lymph nodes of domestic bull are not visualized. In the middle of the lymph nodes parenchyma, its lymphoid lobules are bounded by large capsular trabeculae and peritrebecular sinuses. The parenchyma’s sinuses of the somatic lymph nodes in domestic bull are developed to varying degrees. The maximum capacity is characteristic of peritrabecular sinuses, which are filled with contrast mass firstly, and the minimum capacity is for cortical intermediate sinuses, which leads to uneven intranodal lymphodynamics, or different speed of lymph distribution inside the lymph node parenchyma. As a consequence of the uneven lymph distribution in the lymph node parenchyma’s sinuses is that antigen-presenting cells simultaneously «stimulate» different perisinusoidal sections of the parenchyma from the cortical plateau to the paracortical and medullary cords. The uneven intranodal lymphodynamics of the somatic lymph nodes’ parenchyma in the domestic bull is probably the main reason for the mosaic histoarchitectonics of the organ lymphatic lobules parenchyma with multilevel localization of the lymph nodes. The dynamics of lymph distribution in the lymph nodes parenchyma of a domestic bull has been established, which determines the simultaneous flow of antigens and antigen-presenting cells into different zones of lobule parenchyma, that can be ensuring factor for more effective implementation of the immunobiological function of these organs.

Keywords

• domestic bull