Livers (Jun 2024)

Exploring the Potential Hepatoprotective Properties of Cactus (Cactaceae) in Liver Health and Disease Management: A Brief Review

  • Anne Caroline Alves Vieira,
  • Fabrícia de Souza Ferreira,
  • Januse Míllia Dantas de Araújo,
  • Larissa Maria Gomes Dutra,
  • Kamila Sabino Batista,
  • Angela Maria Tribuzy de Magalhães Cordeiro,
  • Jailane de Souza Aquino

DOI
https://doi.org/10.3390/livers4020021
Journal volume & issue
Vol. 4, no. 2
pp. 287 – 313

Abstract

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Cacti are renowned for their resilience in arid environments and have been utilized as a valuable food source in various cultures for centuries. The potential effects of cactus (Cactaceae) consumption on liver health have garnered significant scientific interest in recent years. This review aimed to consolidate and analyze existing research findings regarding the relationship between cactus-derived compounds and their influence on liver function and health. Various cactus species, particularly Opuntia spp., are rich reservoirs of antioxidants, polyphenols, flavonoids, and betalains. In vitro and in vivo studies with animal models have shown that bioactive constituents of cactus exhibit anti-inflammatory, antioxidative, and antifibrotic properties, which potentially mitigate liver damage induced by oxidative stress, inflammation, and hepatotoxic agents. Understanding their mechanisms of action and conducting rigorous clinical studies with administration of cactus will ascertain their role in preventing and treating liver ailments, offering novel avenues in nutrition, hepatology, and natural medicine.

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