Type 2 Diabetes Mellitus and COVID-19: A Narrative Review

Salvatore Corrao; Salvatore Corrao; Karen Pinelli; Martina Vacca; Massimo Raspanti; Christiano Argano

doi:10.3389/fendo.2021.609470

Frontiers in Endocrinology (Mar 2021)

Type 2 Diabetes Mellitus and COVID-19: A Narrative Review

Salvatore Corrao,
Salvatore Corrao,
Karen Pinelli,
Martina Vacca,
Massimo Raspanti,
Christiano Argano

Affiliations

Salvatore Corrao: Department of Internal Medicine, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy
Salvatore Corrao: Dipartimento di Promozione della Salute, Materno Infantile, Medicina Interna e Specialistica di Eccellenza "G. D'Alessandro", PROMISE, University of Palermo, Palermo, Italy
Karen Pinelli: Department of Internal Medicine, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy
Martina Vacca: Department of Internal Medicine, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy
Massimo Raspanti: Department of Internal Medicine, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy
Christiano Argano: Department of Internal Medicine, National Relevance and High Specialization Hospital Trust ARNAS Civico, Di Cristina, Benfratelli, Palermo, Italy

DOI: https://doi.org/10.3389/fendo.2021.609470
Journal volume & issue: Vol. 12

Abstract

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The pandemic of coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has involved more than one hundred million individuals, including more than two million deaths. Diabetes represents one of the most prevalent chronic conditions worldwide and significantly increases the risk of hospitalization and death in COVID-19 patients. In this review, we discuss the prevalence, the pathophysiological mechanisms, and the outcomes of COVID-19 infection in people with diabetes. We propose a rationale for using drugs prescribed in patients with diabetes and some pragmatic clinical recommendations to deal with COVID-19 in this kind of patient.

Published in Frontiers in Endocrinology

ISSN: 1664-2392 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
Website: https://www.frontiersin.org/journals/endocrinology

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Abstract

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