Nature Communications (Dec 2020)

High-throughput preparation of radioprotective polymers via Hantzsch’s reaction for in vivo X-ray damage determination

  • Guoqiang Liu,
  • Yuan Zeng,
  • Tong Lv,
  • Tengfei Mao,
  • Yen Wei,
  • Shunji Jia,
  • Yanzi Gou,
  • Lei Tao

DOI
https://doi.org/10.1038/s41467-020-20027-0
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 11

Abstract

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Nuclear technology has created a significant interest in developing radio-protectants. Here, the authors combine Hantzsch’s reaction with high-throughput techniques for the development of a polymer radio-protectant and demonstrate protection of cells and zebrafish embryos against ionizing radiation.