An efficient (TBA)2S2O8 catalyzed regioselective solvent-free one-pot synthesis of fully substituted pyrazoles

Mallesh Magini; Sampath Bitla; Muralidhar Reddy Puchakayala; Saritha Birudaraju; Ramulu Dhanavath; Krishnam Raju Atcha

Results in Chemistry (Jan 2021)

An efficient (TBA)2S2O8 catalyzed regioselective solvent-free one-pot synthesis of fully substituted pyrazoles

Mallesh Magini,
Sampath Bitla,
Muralidhar Reddy Puchakayala,
Saritha Birudaraju,
Ramulu Dhanavath,
Krishnam Raju Atcha

Affiliations

Mallesh Magini: Department of Chemistry, Nizam College, Osmania University, Hyderabad, Telangana 500007, India
Sampath Bitla: Department of Chemistry, Nizam College, Osmania University, Hyderabad, Telangana 500007, India
Muralidhar Reddy Puchakayala: Department of Chemistry, University College of Science, Osmania University, Hyderabad, Telangana 500007, India
Saritha Birudaraju: Department of Chemistry, Nizam College, Osmania University, Hyderabad, Telangana 500007, India
Ramulu Dhanavath: Department of Chemistry, Nizam College, Osmania University, Hyderabad, Telangana 500007, India
Krishnam Raju Atcha: Department of Chemistry, Nizam College, Osmania University, Hyderabad, Telangana 500007, India; Corresponding author.

Journal volume & issue: Vol. 3
p. 100184

Abstract

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An efficient tetra-n-butyl ammonium peroxydisulphate (TBA)2S2O8 catalyzed a direct one-pot synthesis of fully substituted pyrazoles in excellent yields with high regioselectivity has been described via a three-component cyclocondensation of aldehydes, aryl hydrazines with β-diketones or β-keto esters under solvent-free conditions. The structure of the target compound 4 m was confirmed by X-ray diffraction.

Published in Results in Chemistry

ISSN: 2211-7156 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Chemistry
Website: https://www.journals.elsevier.com/results-in-chemistry/

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