Nature Communications (Feb 2022)
Circulating microbial content in myeloid malignancy patients is associated with disease subtypes and patient outcomes
- Jakob Woerner,
- Yidi Huang,
- Stephan Hutter,
- Carmelo Gurnari,
- Jesús María Hernández Sánchez,
- Janet Wang,
- Yimin Huang,
- Daniel Schnabel,
- Michael Aaby,
- Wanying Xu,
- Vedant Thorat,
- Dongxu Jiang,
- Babal K. Jha,
- Mehmet Koyuturk,
- Jaroslaw P. Maciejewski,
- Torsten Haferlach,
- Thomas LaFramboise
Affiliations
- Jakob Woerner
- Department of Genetics and Genome Sciences, Case Western Reserve University
- Yidi Huang
- Department of Genetics and Genome Sciences, Case Western Reserve University
- Stephan Hutter
- Munich Leukemia Laboratory
- Carmelo Gurnari
- Department of Translational Hematology & Oncology Research, Cleveland Clinic Foundation
- Jesús María Hernández Sánchez
- Centro de Investigación del Cáncer
- Janet Wang
- Department of Genetics and Genome Sciences, Case Western Reserve University
- Yimin Huang
- Department of Genetics and Genome Sciences, Case Western Reserve University
- Daniel Schnabel
- Department of Genetics and Genome Sciences, Case Western Reserve University
- Michael Aaby
- Department of Genetics and Genome Sciences, Case Western Reserve University
- Wanying Xu
- Department of Genetics and Genome Sciences, Case Western Reserve University
- Vedant Thorat
- Department of Genetics and Genome Sciences, Case Western Reserve University
- Dongxu Jiang
- Department of Translational Hematology & Oncology Research, Cleveland Clinic Foundation
- Babal K. Jha
- Department of Translational Hematology & Oncology Research, Cleveland Clinic Foundation
- Mehmet Koyuturk
- Department of Computer Science, Case Western Reserve University
- Jaroslaw P. Maciejewski
- Department of Translational Hematology & Oncology Research, Cleveland Clinic Foundation
- Torsten Haferlach
- Munich Leukemia Laboratory
- Thomas LaFramboise
- Department of Genetics and Genome Sciences, Case Western Reserve University
- DOI
- https://doi.org/10.1038/s41467-022-28678-x
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 13
Abstract
Circulating microbiome has been very little studied for blood malignancies. Here, the authors show specific microbiome signatures in the blood are associated with different types of myeloid malignancies and specific genetic mutations.
