Nature Communications (Apr 2022)

Boron encapsulated in a liposome can be used for combinational neutron capture therapy

  • Jiyuan Li,
  • Qi Sun,
  • Chuanjie Lu,
  • Han Xiao,
  • Zhibin Guo,
  • Dongban Duan,
  • Zizhu Zhang,
  • Tong Liu,
  • Zhibo Liu

DOI
https://doi.org/10.1038/s41467-022-29780-w
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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Boron neutron capture therapy is a type of cancer therapy but is associated with insufficient boron delivery and with poor biocompatibility. Here, the authors constructed boronated lipids to generate - boronsome - and show the system can reduce tumour growth.