Эпилепсия и пароксизмальные состояния (Sep 2016)

NEW METHODS OF OPTIMIZATION OF EPILEPSY PHARMACOTHERAPY: USE OF BAYESIAN PHARMACOKINETIC MODELING

  • Z. А. Suslina,
  • А. K. Sariev,
  • D. А. Аbaimov,
  • T. YU. Noskova,
  • R. D. Sejfulla,
  • V. V. Shvedkov,
  • D. I. Prokhorov,
  • M. V. Shiryaeva,
  • L. А. Mota

Journal volume & issue
Vol. 4, no. 2
pp. 40 – 47

Abstract

Read online

There was carried out the therapeutic drug monitoring of antiepileptic drug carbamazepine by use of a bayesian mathematical modeling method in 47 patients with a focal epilepsy. The database of patients pharmacokinetic characteristics concerning carbamazepine was created. According the results of carbamazepine monitoring anticonvulsant dosage regimen was corrected

Keywords