Solid-state Synthesis of 1-Ethoxycarbonyl-4-substituted-semicarbazides

Abstract

A rapid and simple method for the preparation of 1-ethoxycarbonyl-4-substituted-semicarbazides has been developed. As examples the reaction of six different isocyanates with ethyl carbazate under solvent-free conditions are reported.

Keywords

• Solid state
• Semicarbazide
• Ethyl carbazate