Perinatal Management for a Pregnant Woman with an MYH9 Disorder

Yuka Yamashita; Rei Matsuura; Shinji Kunishima; Yoshie Oikawa; Hirotsugu Ariizumi; Shoko Hamada; Nahoko Shirato; Ryu Matsuoka; Kohichi Ogawa; Akihiko Sekizawa

doi:10.1155/2016/6730174

Case Reports in Obstetrics and Gynecology (Jan 2016)

Perinatal Management for a Pregnant Woman with an MYH9 Disorder

Yuka Yamashita,
Rei Matsuura,
Shinji Kunishima,
Yoshie Oikawa,
Hirotsugu Ariizumi,
Shoko Hamada,
Nahoko Shirato,
Ryu Matsuoka,
Kohichi Ogawa,
Akihiko Sekizawa

Affiliations

Yuka Yamashita: Department of Obstetrics and Gynecology, Showa University Fujigaoka Hospital, 1-30 Fujigaoka, Aoba-ku, Yokohama 227-8501, Japan
Rei Matsuura: Department of Obstetrics and Gynecology, Showa University Fujigaoka Hospital, 1-30 Fujigaoka, Aoba-ku, Yokohama 227-8501, Japan
Shinji Kunishima: Department of Advanced Diagnosis, Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan
Yoshie Oikawa: Department of Clinical Laboratory, Showa University Fujigaoka Hospital, Yokohama, Japan
Hirotsugu Ariizumi: Department of Hematology, Showa University Fujigaoka Hospital, Yokohama, Japan
Shoko Hamada: Department of Obstetrics and Gynecology, Showa University Fujigaoka Hospital, 1-30 Fujigaoka, Aoba-ku, Yokohama 227-8501, Japan
Nahoko Shirato: Department of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo, Japan
Ryu Matsuoka: Department of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo, Japan
Kohichi Ogawa: Department of Obstetrics and Gynecology, Showa University Fujigaoka Hospital, 1-30 Fujigaoka, Aoba-ku, Yokohama 227-8501, Japan
Akihiko Sekizawa: Department of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo, Japan

DOI: https://doi.org/10.1155/2016/6730174
Journal volume & issue: Vol. 2016

Abstract

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We diagnosed a primipara woman with an MYH9 disorder during her pregnancy. A peripheral blood smear with an immunofluorescence analysis is the established method of diagnosing MYH9 disorders. We provided genetic counseling, as required, which included apprising the woman of the inheritance pattern, the importance of a genetic analysis, and the potential delivery risks for the patient and her offspring. Given that the potential delivery risks are reportedly low, special perinatal management is not necessary for patients with an MYH9 disorder whose platelet count is above 5.0 × 104/μL, except for rapid blood access.

Published in Case Reports in Obstetrics and Gynecology

ISSN: 2090-6684 (Print); 2090-6692 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Gynecology and obstetrics
Website: https://onlinelibrary.wiley.com/journal/7471

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