The landscape of ‘podoplanin’ in dermatology: a narrative review

Abstract

Podoplanin (PDPN) is a specific marker for lymphatic endothelial cells; however, it can be expressed by many other cells including renal podocytes. In dermatology, PDPN has been involved in diverse disorders, such as tumor lymphangiogenesis, as well as in immune-mediated disorders. Herein, we illustrate and discuss the landscape of PDPN in dermatology.

Keywords

• d2-40
• lymphangiogenesis
• lymphatic marker
• metastasis
• podoplanin