Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects

Mathias Rask-Andersen; Torgny Karlsson; Weronica E. Ek; Åsa Johansson

doi:10.1038/s41467-018-08000-4

Nature Communications (Jan 2019)

Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects

Mathias Rask-Andersen,
Torgny Karlsson,
Weronica E. Ek,
Åsa Johansson

Affiliations

Mathias Rask-Andersen: Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University
Torgny Karlsson: Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University
Weronica E. Ek: Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University
Åsa Johansson: Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University

DOI: https://doi.org/10.1038/s41467-018-08000-4
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 10

Abstract

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Obesity and the distribution of fat within the body are risk factors for cardiometabolic diseases. Here, Rask-Andersen et al. perform GWAS for bio-electrical impedance measurements in UK Biobank participants and identify 29 novel independent loci for fat distribution and a high degree of sex-heterogeneity.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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