Giant cell arteritis with eye involvement - color doppler imaging (cdi) of retrobulbar vessels findings

Abstract

Background. Giant cell arteritis is a primary vasculitis, that affects medium-sized arteries, especially branches of the ECA. Purpose. The main objective was to assess the role of CDI of retrobulbar vessels in the study of two patients with Horton’s disease with eye involvement. Methods. We have used a sonographer with 8-15 MHz linear probe for CDI of orbital vessels. Results. Both patients presented malaise, temporal headache, tender temporal arteries and laboratory signs of inflammation. The first patient had a left central retinal artery obstruction, and the second one had a left ischaemic optic neuropathy. They presented a painless, severe loss of vision of the left eye. Temporal artery histology was positive in both cases. Ultrasound investigation was performed before corticosteroid treatement. CDI of retrobulbar vessels detected low blood velocities, especially end-diastolic velocities and high resistance index in all retrobulbar vessels, in both orbits, for both patients (especially on the affected side). Typical sonographic features in temporal arteritis were ”dark halo sign” (vessel wall thickening), associated with stenoses or occlusions of branches of ECA. Interestingly, in both cases, the CCA and the ICA were, also, affected. Conclusions. Ultrasound technique is a valuable diagnostic tool to investigate giant cell arteritis.

Keywords

• giant cell arteritis
• temporal headache
• central retinal artery obstruction
• ischaemic optic neuropathy