Emerging Infectious Diseases (Nov 2011)
Influenza B Viruses with Mutation in the Neuraminidase Active Site, North Carolina, USA, 2010–11
Abstract
Oseltamivir is 1 of 2 antiviral medications available for the treatment of influenza B virus infections. We describe and characterize a cluster of influenza B viruses circulating in North Carolina with a mutation in the neuraminidase active site that may reduce susceptibility to oseltamivir and the investigational drug peramivir but not to zanamivir.
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