Uso de um inibidor da síntese de prostaglandinas em receptoras bovinas com ou sem dificuldade de transposição cervical Use of a synthesis inhibitor of prostaglandins in cattle recipients with or without difficult of cervical manipulation

Abstract

Objetivou-se determinar o efeito do flunixin meglumine sobre a taxa de concepção de receptoras de embriões bovinos com ou sem dificuldade de transposição cervical na inovulação. As receptoras foram distribuídas em quatro grupos experimentais de acordo a dificuldade ou não de transposição cervical e tratamento ou não com flunixin meglumine. Desta forma, os grupos experimentais foram denominados: Não tratadas com flunixin meglumine e sem dificuldade de transposição cervical (S/FM-CF, n=184), não tratadas com flunixin meglumine e com dificuldade de transposição cervical (S/FM-CD, n=58), tratadas com flunixin meglumine e sem dificuldade de transposição cervical (C/FM-CF, n=38) e tratadas com flunixin meglumine e com dificuldade de transposição cervical (C/FM-CD, n=57). As receptoras tratadas com flunixin meglumine receberam uma aplicação de 500mg de flunixin meglumine i.m. (DESFLAN, Ouro Fino, São Paulo, Brasil) imediatamente após as inovulações, enquanto os animais não tratados receberam a aplicação de 10 mL de solução salina fisiológica i.m. A taxa de concepção média foi de 51,93%, já as taxas de concepção dos grupos S/FM-CF, S/FM-CD, C/FM-CF e C/FM-CD foram, respectivamente, de 54,35; 36,21; 50,00 e 61,40%. Verificou-se taxa de concepção significativamente inferior (P=0,007) para as receptoras do grupo S/FM-CD. Os resultados demonstram que o uso do flunixin meglumine pode ser útil em receptoras com dificuldade de transposição cervical, proporcionando o controle do fenômeno de regressão lútea precoce.The aim of this study was to determine the effect of flunixin meglumine on conception rate of bovine embryo recipients with or without difficulty of implementation of the cervix at inovulation. The superovulation and synchronization of donors and recipients were done for this purpose. The recipients were divided into four groups according to difficulty or not for cervical implementation and being treated or not with flunixin meglumine. Thus, experimental groups were named: Not treated with flunixin meglumine and without difficulty of cervical implementation (S/FM-CF, n=184), not treated with flunixin meglumine and with difficulty of cervical implementation (S/FM-CD, n=58), treated with flunixin meglumine and without difficulty of cervical implementation (C/FM-CF, n=38), and treated with flunixin meglumine and with difficulty of cervical implementation (C/FM-CD, n=57). The recipients treated with flunixin meglumine received an application of 500mg flunixin meglumine im (DESFLAN, Ouro Fino, Sao Paulo, Brazil) immediately after the inovulations, while the animals untreated received the application of 10mL of saline solution im. The conception rates average was 51.93%, since the conception rates of the groups S/FM-CF, S/FM-CD, C/FM-CF and C/FM-CD were, respectively, 54.35, 36.21, 50.00 and 61.40%. These results demonstrated a conception rate significantly lower (P=0.007) for recipients from the group S/FM-CD. The results showed that the use of the flunixin meglumine can be helpful in recipients with difficult of implementation of the cervix, providing the control of the phenomenon of early luteal regression.