Urology Case Reports (Sep 2023)

Solitary fibrous tumour of the urinary bladder – A rare and potentially malignant neoplasm

  • Katherine Ong,
  • Shivani Singh,
  • Nicole Swarbrick,
  • Dickon Hayne

Journal volume & issue
Vol. 50
p. 102501

Abstract

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Solitary fibrous tumours (SFTs) of the urinary bladder are a rare mesenchymal neoplasm that occasionally has malignant potential. The tumour is characterised by haphazardly arranged spindle-shaped to ovoid cells, with a prominent, branching, thin-walled, dilated vasculature and NAB2-STAT6 gene rearrangement. While most SFTs are indolent in nature, difficulty arises predicting which SFTs are potentially malignant. There are now validated risk stratification tools to help identify which SFTs are likely to metastasize and help clinicians determine management. The mainstay of treatment for SFTs remains surgery, with emerging evidence in the combined use of surgery and radiotherapy.

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