Genome Medicine (Nov 2018)

The ins and outs of telomere crisis in cancer

  • Patrick von Morgen,
  • John Maciejowski

DOI
https://doi.org/10.1186/s13073-018-0596-4
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 4

Abstract

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Editorial summary Telomere crisis is linked with many of the genomic alterations found in cancer genomes. A new understanding of how these alterations arise points towards an active role for innate immune sensors during crisis and to new opportunities for the treatment and diagnosis of cancer.