Facile and efficient conjugate additions of b-dicarbonyl compounds and nitroalkanes to 4-aryl-4-oxobut-2-enoates

Abstract

Facile and efficient conjugate additions of carbon nucleophiles, such as b-dicarbonyl compounds and nitroalkanes, to 4-aryl-4-oxobut-2-enoates have been achieved under simple base catalysis. A variety of multi-functional g-keto esters could be conveniently obtained in good to excellent yields with complete regioselectivity.

Keywords

• conjugate addition
• multi-functional g-keto ester
• b-dicarbonyl compound
• nitroalkane
• 4-aryl-4-oxobut-2-enoate