Nature Communications (May 2022)
Serotonin limits generation of chromaffin cells during adrenal organ development
- Polina Kameneva,
- Victoria I. Melnikova,
- Maria Eleni Kastriti,
- Anastasia Kurtova,
- Emil Kryukov,
- Aliia Murtazina,
- Louis Faure,
- Irina Poverennaya,
- Artem V. Artemov,
- Tatiana S. Kalinina,
- Nikita V. Kudryashov,
- Michael Bader,
- Jan Skoda,
- Petr Chlapek,
- Lucie Curylova,
- Lukas Sourada,
- Jakub Neradil,
- Marketa Tesarova,
- Massimo Pasqualetti,
- Patricia Gaspar,
- Vasily D. Yakushov,
- Boris I. Sheftel,
- Tomas Zikmund,
- Jozef Kaiser,
- Kaj Fried,
- Natalia Alenina,
- Elena E. Voronezhskaya,
- Igor Adameyko
Affiliations
- Polina Kameneva
- Department of Neuroimmunology, Center for Brain Research, Medical University Vienna
- Victoria I. Melnikova
- Koltsov Institute of Developmental Biology, Russian Academy of Sciences
- Maria Eleni Kastriti
- Department of Neuroimmunology, Center for Brain Research, Medical University Vienna
- Anastasia Kurtova
- Koltsov Institute of Developmental Biology, Russian Academy of Sciences
- Emil Kryukov
- Department of Neuroimmunology, Center for Brain Research, Medical University Vienna
- Aliia Murtazina
- Department of Physiology and Pharmacology, Karolinska Institute
- Louis Faure
- Department of Neuroimmunology, Center for Brain Research, Medical University Vienna
- Irina Poverennaya
- Department of Neuroimmunology, Center for Brain Research, Medical University Vienna
- Artem V. Artemov
- Department of Neuroimmunology, Center for Brain Research, Medical University Vienna
- Tatiana S. Kalinina
- Federal state budgetary institution “Research Zakusov Institute of Pharmacology” (FSBI “Zakusov Institute of Pharmacology”), Russian Academy of Sciences
- Nikita V. Kudryashov
- Federal state budgetary institution “Research Zakusov Institute of Pharmacology” (FSBI “Zakusov Institute of Pharmacology”), Russian Academy of Sciences
- Michael Bader
- Max-Delbrück Center for Molecular Medicine (MDC)
- Jan Skoda
- Department of Experimental Biology, Faculty of Science, Masaryk University
- Petr Chlapek
- Department of Experimental Biology, Faculty of Science, Masaryk University
- Lucie Curylova
- Department of Experimental Biology, Faculty of Science, Masaryk University
- Lukas Sourada
- Department of Experimental Biology, Faculty of Science, Masaryk University
- Jakub Neradil
- Department of Experimental Biology, Faculty of Science, Masaryk University
- Marketa Tesarova
- Central European Institute of Technology, Brno University of Technology
- Massimo Pasqualetti
- Unit of Cell and Developmental Biology, Department of Biology, University of Pisa
- Patricia Gaspar
- INSERM, Paris Brain Institute
- Vasily D. Yakushov
- Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences
- Boris I. Sheftel
- Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences
- Tomas Zikmund
- Central European Institute of Technology, Brno University of Technology
- Jozef Kaiser
- Central European Institute of Technology, Brno University of Technology
- Kaj Fried
- Department of Neuroscience, Karolinska Institute
- Natalia Alenina
- Max-Delbrück Center for Molecular Medicine (MDC)
- Elena E. Voronezhskaya
- Koltsov Institute of Developmental Biology, Russian Academy of Sciences
- Igor Adameyko
- Department of Neuroimmunology, Center for Brain Research, Medical University Vienna
- DOI
- https://doi.org/10.1038/s41467-022-30438-w
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 21
Abstract
Adrenal glands are major organs regulating stress response., Melnikova et al., show that local release of serotonin limits adrenalin-producing cell number during rodent development, a mechanism which has implications for neuroblastoma development and stress-related maternal effects transmitted to progeny.
