Dataset of mitochondrial genome variants associated with asymptomatic atherosclerosis

Margarita A. Sazonova; Andrey V. Zhelankin; Valeria A. Barinova; Vasily V. Sinyov; Zukhra B. Khasanova; Anton Y. Postnov; Igor A. Sobenin; Yuri V. Bobryshev; Alexander N. Orekhov

Data in Brief (Jun 2016)

Dataset of mitochondrial genome variants associated with asymptomatic atherosclerosis

Margarita A. Sazonova,
Andrey V. Zhelankin,
Valeria A. Barinova,
Vasily V. Sinyov,
Zukhra B. Khasanova,
Anton Y. Postnov,
Igor A. Sobenin,
Yuri V. Bobryshev,
Alexander N. Orekhov

Affiliations

Margarita A. Sazonova: Institute of General Pathology and Pathophysiology Russian Academy of Medical Sciences, Moscow, Russian Federation; Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation
Andrey V. Zhelankin: Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation
Valeria A. Barinova: Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation
Vasily V. Sinyov: Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation
Zukhra B. Khasanova: Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation
Anton Y. Postnov: Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation
Igor A. Sobenin: Institute of General Pathology and Pathophysiology Russian Academy of Medical Sciences, Moscow, Russian Federation; Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation
Yuri V. Bobryshev: Institute of General Pathology and Pathophysiology Russian Academy of Medical Sciences, Moscow, Russian Federation; Faculty of Medicine, School of Medical Sciences, University of New South Wales, Sydney, Australia; Corresponding author at: Faculty of Medicine, University of New South Wales, Kensington, NSW 2052, Australia.Tel./fax: +612 93851217.
Alexander N. Orekhov: Institute of General Pathology and Pathophysiology Russian Academy of Medical Sciences, Moscow, Russian Federation; Institute for Atherosclerosis Research, Skolkovo Innovative Centre, Moscow Region, Russian Federation; Department of Biophysics, Biological Faculty, Moscow State University, Moscow, Russian Federation

Journal volume & issue: Vol. 7
pp. 1570 – 1575

Abstract

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This dataset report is dedicated to mitochondrial genome variants associated with asymptomatic atherosclerosis. These data were obtained using the method of next generation pyrosequencing (NGPS). The whole mitochondrial genome of the sample of patients from the Moscow region was analyzed. In this article the dataset including anthropometric, biochemical and clinical parameters along with detected mtDNA variants in patients with carotid atherosclerosis and healthy individuals was presented. Among 58 of the most common homoplasmic mtDNA variants found in the observed sample, 7 variants occurred more often in patients with atherosclerosis and 16 variants occurred more often in healthy individuals. Keywords: mtDNA variant, Mitochondrial genome, Homoplasmic, Asymptomatic atherosclerosis

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

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