Emerging Infectious Diseases (Oct 2007)

Chlorine Inactivation of Highly Pathogenic Avian Influenza Virus (H5N1)

  • Eugene W. Rice,
  • Noreen J. Adcock,
  • Mano Sivaganesan,
  • Justin D. Brown,
  • David E. Stallknecht,
  • David E. Swayne

DOI
https://doi.org/10.3201/eid1310.070323
Journal volume & issue
Vol. 13, no. 10
pp. 1568 – 1570

Abstract

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To determine resistance of highly pathogenic avian influenza (H5N1) virus to chlorination, we exposed allantoic fluid containing 2 virus strains to chlorinated buffer at pH 7 and 8, at 5°C. Free chlorine concentrations typically used in drinking water treatment are sufficient to inactivate the virus by >3 orders of magnitude.

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