Acta Crystallographica Section E (Apr 2012)

Fluphenazine dihydrochloride dimethanol solvate

  • Joanna Petrus,
  • Rafał Petrus,
  • Bogusława Czarnik-Matusewicz

DOI
https://doi.org/10.1107/S1600536812008707
Journal volume & issue
Vol. 68, no. 4
pp. o1004 – o1005

Abstract

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In the title compound {systematic name: 1-(2-hydroxyethyl)-4-[3-(2-trifluoromethyl-10H-phenothiazin-10-yl)propyl]piperazine-1,4-diium dichloride dimethanol disolvate}, C22H28F3N3OS2+·2Cl−·2CH3OH, the dihedral angle between the planes of the two outer benzene rings of the tricyclic phenothiazine system is 46.91 (13)°. The piperazine ring adopts a chair conformation. The crystal structure is stabilized by O—H...Cl, N—H...Cl, C—H...O, C—H...Cl and C—H...F hydrogen bonds and contacts.