AIDS Research and Therapy (Jun 2022)

A pilot pragmatic trial of a “what matters most”-based intervention targeting intersectional stigma related to being pregnant and living with HIV in Botswana

  • Lawrence H. Yang,
  • Evan L. Eschliman,
  • Haitisha Mehta,
  • Supriya Misra,
  • Ohemaa B. Poku,
  • Patlo Entaile,
  • Timothy D. Becker,
  • Tadele Melese,
  • Merrian J. Brooks,
  • Marlene Eisenberg,
  • Melissa A. Stockton,
  • Karen Choe,
  • Danielle Tal,
  • Tingyu Li,
  • Vivian F. Go,
  • Bruce G. Link,
  • Shathani Rampa,
  • Valerie W. Jackson,
  • Gorata D. Manyeagae,
  • Tonya Arscott-Mills,
  • Melody Goodman,
  • Philip R. Opondo,
  • Ari R. Ho-Foster,
  • Michael B. Blank

DOI
https://doi.org/10.1186/s12981-022-00454-3
Journal volume & issue
Vol. 19, no. 1
pp. 1 – 11

Abstract

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Abstract We conducted a pilot trial of an intervention targeting intersectional stigma related to being pregnant and living with HIV while promoting capabilities for achieving ‘respected motherhood’ (‘what matters most’) in Botswana. A pragmatic design allocated participants to the intervention (N = 44) group and the treatment-as-usual (N = 15) group. An intent-to-treat, difference-in-difference analysis found the intervention group had significant decreases in HIV stigma (d = − 1.20; 95% CI − 1.99, − 0.39) and depressive symptoms (d = − 1.96; 95% CI − 2.89, − 1.02) from baseline to 4-months postpartum. Some, albeit less pronounced, changes in intersectional stigma were observed, suggesting the importance of structural-level intervention components to reduce intersectional stigma.

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