Nature Communications (Feb 2018)
Sculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement
- Y. Z. Shi,
- S. Xiong,
- Y. Zhang,
- L. K. Chin,
- Y. –Y. Chen,
- J. B. Zhang,
- T. H. Zhang,
- W. Ser,
- A. Larrson,
- S. H. Lim,
- J. H. Wu,
- T. N. Chen,
- Z. C. Yang,
- Y. L. Hao,
- B. Liedberg,
- P. H. Yap,
- K. Wang,
- D. P. Tsai,
- C.-W. Qiu,
- A. Q. Liu
Affiliations
- Y. Z. Shi
- School of Mechanical Engineering, Xi’an Jiaotong University
- S. Xiong
- School of Electrical and Electronic Engineering, Nanyang Technological University
- Y. Zhang
- School of Mechanical and Aerospace Engineering, Nanyang Technological University
- L. K. Chin
- School of Electrical and Electronic Engineering, Nanyang Technological University
- Y. –Y. Chen
- School of Electrical and Electronic Engineering, Nanyang Technological University
- J. B. Zhang
- School of Electrical and Electronic Engineering, Nanyang Technological University
- T. H. Zhang
- Department of Electrical and Computer Engineering, National University of Singapore
- W. Ser
- School of Electrical and Electronic Engineering, Nanyang Technological University
- A. Larrson
- School of Biological Sciences, Nanyang Technological University
- S. H. Lim
- School of Biological Sciences, Nanyang Technological University
- J. H. Wu
- School of Mechanical Engineering, Xi’an Jiaotong University
- T. N. Chen
- School of Mechanical Engineering, Xi’an Jiaotong University
- Z. C. Yang
- National Key Laboratory of Science and Technology on Micro/Nano Fabrication, Institute of Microelectronics, Peking University
- Y. L. Hao
- National Key Laboratory of Science and Technology on Micro/Nano Fabrication, Institute of Microelectronics, Peking University
- B. Liedberg
- Centre for Biomimetic Sensor Science, School of Materials Science and Engineering, Nanyang Technological University
- P. H. Yap
- Lee Kong Chian School of Medicine, Nanyang Technological University
- K. Wang
- College of Biomedical Engineering, Taipei Medical University
- D. P. Tsai
- Department of Physics, National Taiwan University
- C.-W. Qiu
- Department of Electrical and Computer Engineering, National University of Singapore
- A. Q. Liu
- School of Electrical and Electronic Engineering, Nanyang Technological University
- DOI
- https://doi.org/10.1038/s41467-018-03156-5
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 11
Abstract
Optical trapping is a versatile tool for biomedical applications. Here, the authors use an optofluidic lattice to achieve controllable multi-particle hopping and demonstrate single-bacteria-level screening and measurement of binding efficiency of biological binding agents through particle-enabled bacteria hopping.
