Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast

Daniel C. Jeffares; Clemency Jolly; Mimoza Hoti; Doug Speed; Liam Shaw; Charalampos Rallis; Francois Balloux; Christophe Dessimoz; Jürg Bähler; Fritz J. Sedlazeck

doi:10.1038/ncomms14061

Nature Communications (Jan 2017)

Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast

Daniel C. Jeffares,
Clemency Jolly,
Mimoza Hoti,
Doug Speed,
Liam Shaw,
Charalampos Rallis,
Francois Balloux,
Christophe Dessimoz,
Jürg Bähler,
Fritz J. Sedlazeck

Affiliations

Daniel C. Jeffares: Department of Genetics, Evolution and Environment, University College London
Clemency Jolly: Department of Genetics, Evolution and Environment, University College London
Mimoza Hoti: Department of Genetics, Evolution and Environment, University College London
Doug Speed: UCL Genetics Institute, University College London
Liam Shaw: Department of Genetics, Evolution and Environment, University College London
Charalampos Rallis: Department of Genetics, Evolution and Environment, University College London
Francois Balloux: Department of Genetics, Evolution and Environment, University College London
Christophe Dessimoz: Department of Genetics, Evolution and Environment, University College London
Jürg Bähler: Department of Genetics, Evolution and Environment, University College London
Fritz J. Sedlazeck: Department of Computer Science, Johns Hopkins University

DOI: https://doi.org/10.1038/ncomms14061
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 11

Abstract

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Fission yeastSchizosaccharomyces pombe has diverse traits. Jeffares et al. characterize large copy number variations (CNVs) and rearrangements in S. pombe, and show that CNVs are transient with effects on quantitative traits and gene expression, whereas rearrangements influence intrinsic reproductive isolation.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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