Cleft Palate in Infants Exposed to Lamotrigine During Pregnancy

Abstract

Infants with major malformations bom to 791 women who had taken lamotrigine as monotherapy during the first trimester of pregnancy, and had enrolled in the North American AED Pregnancy Registry, were identified in a study at the Genetics and Teratology Unit, MassGeneral Hospital for Children, Boston, and Boston University School of Medicine, MA.

Keywords

• isolated cleft palate
• isolated cleft lip
• anticonvulsant lamotrigine