Heliyon (Mar 2024)

Associations between sleep problems and cardiometabolic risk in maintenance hemodialysis patients: A multicenter study

  • Huan Yang,
  • Yingxin Zhang,
  • Xiuyong Li,
  • Zhi Liu,
  • Youwei Bai,
  • Guangrong Qian,
  • Han Wu,
  • Ji Li,
  • Yuwen Guo,
  • Shanfei Yang,
  • Lei Chen,
  • Jian Yang,
  • Jiuhuai Han,
  • Shengyin Ma,
  • Jing Yang,
  • Linfei Yu,
  • Runzhi Shui,
  • Xiping Jin,
  • Hongyu Wang,
  • Fan Zhang,
  • Tianhao Chen,
  • Xinke Li,
  • Xiaoying Zong,
  • Li Liu,
  • Jihui Fan,
  • Wei Wang,
  • Yong Zhang,
  • Guangcai Shi,
  • Deguang Wang,
  • Shuman Tao

Journal volume & issue
Vol. 10, no. 6
p. e27377

Abstract

Read online

The incidence of cardiovascular disease is increasing around the world, and it is one of the main causes of death in chronic kidney diseases patients. It is urgent to early identify the factors of cardiometabolic risk. Sleep problems have been recognized as a risk factor for cardiometabolic risk in both healthy people and chronic patients. However, the relationship between sleep problems and cardiometabolic risk has not been clearly explored in hemodialysis patients. This study aimed to investigate the relationship between sleep problems and cardiometabolic risk in 3025 hemodialysis patients by a multicenter study. After adjusting for confounders, binary logistic regression models showed that hemodialysis patients reported sleep duration greater than 7 h were more likely to be with hypertension, hyperglycemia, hypertriglyceridemia, and hypercholesterolemia. Patients reported sleep duration less than 7 h were more likely to be with hypertriglyceridemia and hypercholesterolemia, but the risks of hyperglycemia and Low HDL-cholesterol were decreased. Poor sleep quality was negatively correlated to low HDL cholesterol and hypertriglyceridemia. Moreover, gender-based differences were explained.

Keywords