The Effect of 4 Weeks Plyometric Training on Alterations in Serum Levels of Brain- Derived Neurotrophic Factor, MDA And SOD in Active Men

Abstract

Purpose: The objective of this study was to investigate the alterations of Serum levels of brain derived neurotrophicfactor, and oxidative stress following a period of plyometric training in active men. Methods: Fourteen healthy activemale students randomly divided into two groups: training (mean age 22.14±1.34 years, height 172.14±3.89 cm, weight63.42±8.77 kg, BMI 21.42±2.77 kg/m2) and control (mean age 23.85±2.54 years, height 178.57±7.11 cm, weight71.71±4.53 kg, BMI 22.60±1.90 kg/m2). Training group performed 4 weeks of plyometric training. BDNF,malondialdehyde and superoxide dismutase activity was measured. Paired sample t-test was used to examine differenceswithin groups, and independent t-test was utilized to examine differences between groups. Differences were considered tobe significant when p 0.05) compared with before training, whereas serum levels of SOD and MDA increased significantly(P=0.002, P=0.036, respectively). BDNF and MDA did not change significantly between control and training groupsfollowing 4 weeks of plyometric training (P> 0.05) but caused a significant increase in serum levels of SOD (P= 0.049).Conclusions: The findings of the present study indicate no significant changes in BDNF levels following regularplyometric training. Regarding increased lipid peroxidation index values in within group and lack of any changes inbetween group, can not accurate conclusion about the possible antioxidant role of BDNF against stress induced byphysical activity, so needs to more investigations.

Keywords

• brain-derived neurotrophic factor
• malondialdehyde
• superoxide dismutase
• plyometric training