Антибиотики и Химиотерапия (May 2020)

Studying the Effectiveness of Ridostin® in the Experimental Form of Severe Acute Respiratory Syndrome

  • S. Ya. Loginova,
  • V. N. Shchukina,
  • S. V. Borisevich,
  • R. A. Hamitov,
  • V. A. Maksimov

DOI
https://doi.org/10.1016/0235-2990-2019-64-11-12-31-34
Journal volume & issue
Vol. 64, no. 11-12
pp. 31 – 34

Abstract

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Studies have been carried out on the effectiveness of the high molecular weight interferon inducer Ridostin® in relation to the experimental form of severe acute respiratory syndrome in Syrian hamsters. It is shown that Ridostin® is effective when used according to the prophylaxis regimen and post-exposure prophylaxis regimen. The coefficient of therapeutic effect was 47.5 and 55.0%, respectively. At the same time, there was a statistically high level of significant differences in the severity of the disease in animals treated with the medication according to the post-exposure prophylaxis regimen and control animals (P

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