Smart-watch-programmed green-light-operated percutaneous control of therapeutic transgenes

Maysam Mansouri; Marie-Didiée Hussherr; Tobias Strittmatter; Peter Buchmann; Shuai Xue; Gieri Camenisch; Martin Fussenegger

doi:10.1038/s41467-021-23572-4

Nature Communications (Jun 2021)

Smart-watch-programmed green-light-operated percutaneous control of therapeutic transgenes

Maysam Mansouri,
Marie-Didiée Hussherr,
Tobias Strittmatter,
Peter Buchmann,
Shuai Xue,
Gieri Camenisch,
Martin Fussenegger

Affiliations

Maysam Mansouri: Department of Biosystems Science and Engineering, ETH Zurich
Marie-Didiée Hussherr: Department of Biosystems Science and Engineering, ETH Zurich
Tobias Strittmatter: Department of Biosystems Science and Engineering, ETH Zurich
Peter Buchmann: Department of Biosystems Science and Engineering, ETH Zurich
Shuai Xue: Department of Biosystems Science and Engineering, ETH Zurich
Gieri Camenisch: Department of Biosystems Science and Engineering, ETH Zurich
Martin Fussenegger: Department of Biosystems Science and Engineering, ETH Zurich

DOI: https://doi.org/10.1038/s41467-021-23572-4
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 10

Abstract

Read online

Wearable smart devices often have green light diodes to monitor health. Here the authors use this to control a light-activated genetic switch for GLP1 production in diabetic mice.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal