Systemic risk factors for developing of primary open-angle glaucoma

Abstract

E.A. Egorov1, V.P. Erichev2, A.L. Onishchenko3, S.Yu. Petrov2, A.V. Kuroyedov1,4, A.A. Antonov2, A.A. Vitkov5 1 Pirogov Russian National Research Medical University, Moscow, Russian Federation 2 Scientific Research Institute of Eye Diseases, Moscow, Russian Federation 3 Novokuznetsk State Institute of Postgraduate Medicine — branch of Russian Medical  Academy of Continuous Professional Education, Russian Federation 4 Central Military Clinical Hospital named after P. V. Mandryka, Moscow, Russian Federation 5 Sechenov University, Moscow, Russian Federation Abstract Primary open-angle glaucoma (POAG) is a disease that manifests itself in the late stages and leads to irreversible vision loss. Regular preventive examinations of the population contribute to the timely detection of patients with early stages of glaucoma, as well as the formation of risk groups based on medical history. The presence of concomitant systemic disease is an important risk factor, which can lead to the development or progression of glaucoma.  Currently, there are many studies, devoted to examination of the possible relationship between systemic diseases and glaucoma. Diabetes mellitus and arterial hypertension are considered to be the most studied systemic risk factors. There is the evidence of the possible impact of hypothyroidism and obesity on the resistance of outflow of intraocular fluid and increase in intraocular pressure. The aim of this review is to summarize current data on systemic risk factors for POAG, which can contribute to a better understanding of the principles of glaucoma and to plan diagnostics taking into account the assessment of all risks. Such an approach will help to timely diagnose glaucoma and prevent irreversible irreversible vision loss. Key words: primary open-angle glaucoma, risk factors, diabetes mellitus, arterial hypertension, hypothyroidism, obesity, Helicobacter pylori. For citation: Egorov E.A., Erichev V.P., Onishchenko A.L. et al. Systemic risk factors for developing of primary open-angle glaucoma. RMJ “Clinical ophthalmology”. 2018;3:140–145.