Nature Communications (Jun 2022)

Defect engineering of layered double hydroxide nanosheets as inorganic photosensitizers for NIR-III photodynamic cancer therapy

  • Weicheng Shen,
  • Tingting Hu,
  • Xueyan Liu,
  • Jiajia Zha,
  • Fanqi Meng,
  • Zhikang Wu,
  • Zhuolin Cui,
  • Yu Yang,
  • Hai Li,
  • Qinghua Zhang,
  • Lin Gu,
  • Ruizheng Liang,
  • Chaoliang Tan

DOI
https://doi.org/10.1038/s41467-022-31106-9
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

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Defect engineering of 2 dimensional layered double hydroxide sheets improves their photocatalytic activity. Here, the authors etch sheets in acid and show that the etched sheets generate substantially more reactive oxygen species that untreated sheets and the treated sheets can be used to kill cancer cells in vitro and in vivo.