Communications Biology (Sep 2022)
LDLR, LRP1, and Megalin redundantly participate in the uptake of Clostridium novyi alpha-toxin
Abstract
Clostridium novyi alpha-toxin (Tcnα) also uses LRP1 and Megalin as cellular entry receptors besides LDLR, and this might be a response to cell-type dependent receptor availability for the exotoxin.