International Journal of Molecular Sciences (Jan 2022)

The Versatility in the Applications of Dithiocarbamates

  • Timothy O. Ajiboye,
  • Titilope T. Ajiboye,
  • Riadh Marzouki,
  • Damian C. Onwudiwe

DOI
https://doi.org/10.3390/ijms23031317
Journal volume & issue
Vol. 23, no. 3
p. 1317

Abstract

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Dithiocarbamate ligands have the ability to form stable complexes with transition metals, and this chelating ability has been utilized in numerous applications. The complexes have also been used to synthesize other useful compounds. Here, the up-to-date applications of dithiocarbamate ligands and complexes are extensively discussed. Some of these are their use as enzyme inhibitor and treatment of HIV and other diseases. The application as anticancer, antimicrobial, medical imaging and anti-inflammatory agents is examined. Moreover, the application in the industry as vulcanization accelerator, froth flotation collector, antifouling, coatings, lubricant additives and sensors is discussed. The various ways in which they have been employed in synthesis of other compounds are highlighted. Finally, the agricultural uses and remediation of heavy metals via dithiocarbamate compounds are comprehensively discussed.

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