Nonperturbative Fluorogenic Labeling of Immunophilins Enables the Wash-free Detection of Immunosuppressants

• Marco Bertolini,
• Lorena Mendive-Tapia,
• Ouldouz Ghashghaei,
• Abigail Reese,
• Charles Lochenie,
• Anna M. Schoepf,
• Miquel Sintes,
• Karolina Tokarczyk,
• Zandile Nare,
• Andrew D. Scott,
• Stephen R. Knight,
• Advait R. Aithal,
• Amit Sachdeva,
• Rodolfo Lavilla,
• Marc Vendrell

Affiliations

Marco Bertolini

Centre for Inflammation Research, The University of Edinburgh, Edinburgh, U.K.

Lorena Mendive-Tapia

Centre for Inflammation Research, The University of Edinburgh, Edinburgh, U.K.

Ouldouz Ghashghaei

Laboratory of Medicinal Chemistry, Faculty of Pharmacy and Food Sciences and Institute of Biomedicine UB (IBUB), University of Barcelona, Catalunya, Spain

Abigail Reese

Centre for Inflammation Research, The University of Edinburgh, Edinburgh, U.K.

Charles Lochenie

Centre for Inflammation Research, The University of Edinburgh, Edinburgh, U.K.

Anna M. Schoepf

Laboratory of Medicinal Chemistry, Faculty of Pharmacy and Food Sciences and Institute of Biomedicine UB (IBUB), University of Barcelona, Catalunya, Spain

Miquel Sintes

Laboratory of Medicinal Chemistry, Faculty of Pharmacy and Food Sciences and Institute of Biomedicine UB (IBUB), University of Barcelona, Catalunya, Spain

Karolina Tokarczyk

Concept Life Sciences Ltd, Edinburgh Bioquarter, Edinburgh, U.K.

Zandile Nare

Concept Life Sciences Ltd, Edinburgh Bioquarter, Edinburgh, U.K.

Andrew D. Scott

Concept Life Sciences Ltd, Edinburgh Bioquarter, Edinburgh, U.K.

Stephen R. Knight

Renal Transplant Unit, Queen Elizabeth Hospital, Glasgow, U.K.

Advait R. Aithal

School of Chemistry, University of East Anglia, Norwich, U.K.

Amit Sachdeva

School of Chemistry, University of East Anglia, Norwich, U.K.

Rodolfo Lavilla

Laboratory of Medicinal Chemistry, Faculty of Pharmacy and Food Sciences and Institute of Biomedicine UB (IBUB), University of Barcelona, Catalunya, Spain

Marc Vendrell

Centre for Inflammation Research, The University of Edinburgh, Edinburgh, U.K.