Nature Communications (Apr 2020)

Nitrogen limitation reveals large reserves in metabolic and translational capacities of yeast

  • Rosemary Yu,
  • Kate Campbell,
  • Rui Pereira,
  • Johan Björkeroth,
  • Qi Qi,
  • Egor Vorontsov,
  • Carina Sihlbom,
  • Jens Nielsen

DOI
https://doi.org/10.1038/s41467-020-15749-0
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

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Cells maintain reserves in their metabolic and translational capacities enabling fast response to changing environments. Here, the authors quantify reserves in yeast by stepwise reduction in nitrogen availability and a combination of multi-omic analysis and metabolic modelling.